Equine protozoal myeloencephalitis (EPM) is a debilitating neurological disease affecting horses, caused by the protozoan parasite Sarcocystis neurona, typically transmitted by opossums. EPM can lead to muscle atrophy, weakness, incoordination, lameness, and, in severe cases, paralysis or death. Traditional treatments such as sulfadiazine and pyrimethamine can be ineffective and carry significant side effects. Enter Toltrazuril,