Equine Protozoal Myeloencephalitis (EPM) is a serious neurological condition in horses, caused by the protozoan parasite Sarcocystis neurona. If left untreated, EPM can lead to irreversible neurological damage and even death. Fortunately, two medications—Ponazuril and Diclazuril—are proven to be highly effective in treating EPM. In this blog post, we’ll explore the use of Ponazuril 10% and Diclazuril in treating EPM, discuss their dosage guidelines, provide insights on where to buy them at competitive prices, and direct you to trusted sources like Toltrazuril Shop.com for purchasing.
Ponazuril 10% for EPM Treatment
Ponazuril is one of the leading treatment options for EPM in horses, known for its ability to target and eliminate the protozoa causing the disease. Ponazuril is a derivative of toltrazuril, another antiparasitic compound used in veterinary medicine. Its mechanism of action disrupts the reproduction cycle of Sarcocystis neurona, effectively reducing the protozoal load in the horse’s system, which leads to an improvement in neurological symptoms.
Effectiveness of Ponazuril in Treating EPM
One of Ponazuril’s major benefits is its ability to cross the blood-brain barrier, which allows it to reach the site of the infection in the central nervous system. This is crucial because Sarcocystis neurona often invades the brain and spinal cord, leading to the characteristic neurological symptoms of EPM such as ataxia (loss of coordination), muscle atrophy, and even seizures in severe cases.
Clinical studies have demonstrated that Ponazuril 10% significantly improves the chances of recovery when administered early in the course of the disease. With its powerful effects, Ponazuril is frequently used as a first-line treatment option for horses diagnosed with EPM. However, like all medications, the correct dosage is critical for its effectiveness.
Ponazuril Dosage Chart for Horses
The recommended dosage for Ponazuril in horses depends on the weight of the animal. The general guideline for Ponazuril 10% is 5 mg/kg of body weight, administered once daily for a period of 28 days. Here’s a sample dosage chart to guide you:
| Horse Weight | Ponazuril Dosage (ml) |
|---|---|
| 500 kg | 25 ml |
| 600 kg | 30 ml |
| 700 kg | 35 ml |
| 800 kg | 40 ml |
The duration of the treatment may vary depending on the horse’s response, and some veterinarians recommend an extended course for horses with severe EPM symptoms. Always consult your vet for personalized dosage recommendations, especially if your horse has other health issues.
Where to Buy Ponazuril for EPM
When purchasing Ponazuril for EPM, it’s essential to choose a reputable supplier. Ponazuril is available in various concentrations, but Ponazuril 10% is commonly used for EPM. You can buy Ponazuril 10% at Toltrazuril Shop.com, where you’ll find competitive prices and assured product quality.
Diclazuril for EPM: Price and Availability
Diclazuril is another potent antiprotozoal agent used in the treatment of EPM. Like Ponazuril, it works by interfering with the protozoan’s ability to reproduce, leading to its eventual elimination from the horse’s system. Although it’s less commonly prescribed than Ponazuril, Diclazuril is an excellent alternative for horses that may not respond to Ponazuril or for horse owners looking for a cost-effective option.
Benefits of Diclazuril for EPM Treatment
One of the main advantages of Diclazuril is that it is considered safe for long-term use in horses. This makes it an excellent option for horses that require prolonged treatment or maintenance therapy to prevent relapse. Diclazuril is also praised for its ease of administration, available in oral paste or pellet formulations, making it easy for horse owners to administer during their horse’s treatment regimen.
Diclazuril Price for EPM Treatment
Diclazuril is generally more affordable than Ponazuril, though the price can vary depending on the supplier. The cost of Diclazuril ranges from $150 to $300 for a month’s supply, depending on the concentration and formulation. For the best prices, Toltrazuril Shop.com offers competitive rates and bulk purchase options.
Availability of Diclazuril at Toltrazuril Shop.com
At Toltrazuril Shop.com, Diclazuril is available in various formulations tailored for easy administration and optimal treatment outcomes. Customers can select from oral pastes, pellets, or powder depending on their horse’s needs. Toltrazuril Shop.com ensures that you’re receiving genuine products that meet veterinary standards for treating EPM in horses.
Where to Buy Ponazuril and Diclazuril Online
When treating a serious condition like EPM, it’s crucial to obtain medication from a trusted and reputable source. Buying Ponazuril and Diclazuril online can be challenging, but Toltrazuril Shop.com makes the process simple and secure.
Why Choose Toltrazuril Shop.com?
- Competitive Pricing: Toltrazuril Shop.com offers both Ponazuril 10% and Diclazuril at prices that are more affordable than many other suppliers. Their competitive pricing ensures that you’re not overpaying for essential treatments.
- Quality Assurance: The products sold on Toltrazuril Shop.com are certified and sourced from trusted manufacturers, so you can rest assured that your horse is receiving high-quality, effective treatment.
- Fast Shipping: Toltrazuril Shop.com offers quick and reliable shipping options to ensure that your medications arrive on time, minimizing any delay in treatment.
- Customer Support: If you have any questions regarding dosage or product selection, the team at Toltrazuril Shop.com is available to assist you. Their customer support ensures you make an informed decision about your horse’s treatment.
How to Purchase Ponazuril and Diclazuril from Toltrazuril Shop.com
Purchasing Ponazuril or Diclazuril is easy. Simply visit Toltrazuril Shop.com, select the product you need, and complete the checkout process. They offer a variety of payment methods, and you can track your shipment once your order has been placed.
For added convenience, the website offers detailed product descriptions, including dosage guidelines and administration instructions, so you’ll have all the information you need at your fingertips.
Conclusion
Equine Protozoal Myeloencephalitis (EPM) is a challenging disease, but with the right treatment, your horse can make a full recovery. Ponazuril and Diclazuril are two of the most effective treatments available, with proven success in eliminating the protozoal infection and improving neurological function. Whether you choose Ponazuril 10% or Diclazuril, both medications are available at Toltrazuril Shop.com at competitive prices.
For horse owners looking to secure the best treatment options for their animals, Ponazuril and Diclazuril offer a reliable path to recovery from EPM. Be sure to consult with your veterinarian to determine the best course of treatment, and visit Toltrazuril Shop.com for all your EPM medication needs.
