Equine Protozoal Myeloencephalitis (EPM) is a debilitating neurological disease affecting horses, caused by the protozoal parasites Sarcocystis neurona or Neospora hughesi. EPM can lead to severe symptoms, including muscle atrophy, lack of coordination, and weakness, often affecting a horse’s performance and overall well-being. Early and effective treatment is crucial to managing this disease, and Ponazuril